synthesis and characterization of biodegradable semi-interpenetrating polymer networks based on star-shaped copolymers of ɛ-caprolactone and lactide

Authors

ali hossein rezayan department of life science engineering, faculty of new sciences & technologies, university of tehran, north karegar st., tehran, 14399-55941, iran

negar firoozi department of life science engineering, faculty of new sciences and technologies, university of tehran, p.o. box 14395-1561, fax +982188617087,tehran, iran

somayyeh kheirjou university of tehran

seyed jamal tabatabaei rezaei department of chemistry, faculty of science, university of zanjan, p.o. box 45195-313, zanjan, iran

abstract

in this paper, the focus is on a new kind of biodegradable semi-interpenetrating polymer networks, which derived from ɛ-caprolactone, lactide, 1,4-butane diisocyanate and ethylenediamine and also its potential has been investigated in soft tissue engineering applications. the polymers were characterized by nuclear magnetic resonance (nmr) spectrometry, fourier transform infrared spectroscopy (ft-ir), differential thermal analysis (dta), differential scanning calorimetry (dsc) and thermogravimetric analysis (tga). these experiments show that the polymers with the right composition and the expected molecular weight were achieved. also, the in vitro degradation of polymer network was examined in phosphate buffer solutions (ph 7.4) at 37 °c. in addition, cell viability and adhesion tests were carried out with fibroblast cells by the mtt assay, which confirmed biocompatibility. polyurethane materials have superior mechanical properties, so these biodegradable and biocompatible films demonstrate potential for future application as cell scaffolds in soft tissue engineering applications.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Synthesis and Characterization of Biodegradable Semi-Interpenetrating Polymer Networks Based on Star-Shaped Copolymers of ɛ-Caprolactone and Lactide

In this paper, the focus is on a new kind of biodegradable semi-interpenetrating polymer networks, which derived from ɛ-caprolactone, lactide, 1,4-butane diisocyanate and ethylenediamine and also its potential has been investigated in soft tissue engineering applications. The polymers were characterized by nuclear magnetic resonance (NMR) spectrometry, fourier transform infrared spectroscopy (F...

full text

Synthesis and Characterization of Biodegradable Semi-Interpenetrating Polymer Networks Based on Star-Shaped Copolymers of ɛ-Caprolactone and Lactide

In this paper, the focus is on a new kind of biodegradable semi-interpenetrating polymer networks, which derived from ɛ-caprolactone, lactide, 1,4-butane diisocyanate and ethylenediamine and also its potential has been investigated in soft tissue engineering applications. The polymers were characterized by nuclear magnetic resonance (NMR) spectrometry, fourier transform infrared spectroscopy (F...

full text

Synthesis and Characterization of Biodegradable Semi-Interpenetrating Polymer Networks Based on Star-Shaped Copolymers of ɛ-Caprolactone and Lactide

In this paper, the focus is on a new kind of biodegradable semi-interpenetrating polymer networks, which is derived from ɛ-caprolactone, lactide, 1,4-butane diisocyanate and ethylenediamine and also its potential has been investigated in soft tissue engineering applications. The polymers were characterized by nuclear magnetic resonance (NMR) spectrometry, Fourier transform infrared spectroscopy...

full text

synthesis and characterization of some macrocyclic schiff bases

ماکروسیکلهای شیف باز از اهمیت زیادی در شیمی آلی و دارویی برخوردار می باشند. این ماکروسیکلها با دارابودن گروه های مناسب در مکانهای مناسب می توانند فلزاتی مثل مس، نیکل و ... را در حفره های خود به دام انداخته، کمپلکسهای پایدار تولید نمایند. در این پایان نامه ابتدا یک دی آلدئید آروماتیک از گلیسیرین تهیه می شود و در مرحله بعدی واکنش با دی آمینهای آروماتیک و یا آلیفاتیک در رقتهای بسیار زیاد منجر به ت...

15 صفحه اول

extraction and characterization of allium irancum plant extract and its application in the green synthesis of silver nano particles and oxidation of thiocarbony1 compounds

سنتز سبز نانوذرات فلزی (nps) درسالهای اخیر توجه بسیارزیادی را به خود جلب کرده است. زیرا این پروتوکل کم هزینه وسازگار با محیط زیست از روش های استاندارد سنتز. در این پایان نامه ما گزارش میکنیم یک روش ساده و سازگار با محیط زیست برای سنتز نانوذرات نقره با استفاده از محلول آبی عصاره گیاه allium iranicum به عنوان یک عامل کاهش دهنده ی طبیعی. نانو ذرات نقره مشخص شد با استفاده از تکنیک های uv-visible، x...

synthesis and characterization of potentially biological active cyclometallated organoplatinum(ii) complexes

this work is presented in five parts. in the first part preparation of the starting complex [pt(c^n)cl(dmso)], 1, in which c^n = n(1),c(2?)-chelated, deprotonated 2-phenylpyridine, and dmso = dimethylsulfoxide, and its reaction with 1 equiv of the biphosphine ligands bis(diphenylphosphino)amine, dppa, or bis(diphenylphosphino)methane, dppm, to give the complex [pt(c^n)cl(dppa)], 2, or [pt(c^n)c...

15 صفحه اول

My Resources

Save resource for easier access later


Journal title:
iranian journal of pharmaceutical research

جلد ۱۶، شماره ۱، صفحات ۶۳-۷۳

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023